Figures & data
Table I. Structural details of sulfonamides/sulfamates used in the present study.
Table II. PRECLAV descriptors used in the significant models.
Table III. Quantum and Chemical descriptors computed by HyperChem used in the present study.
Table IV. Statically significant models for the set of 28 compounds using PRECLAV parameters.
Table V. Statically significant models for the set of 28 compounds using HyperChem descriptors.
Table VI. Observed and estimated values of log hCAXIV their residue(for 28 compound's) using 4-varible models obtained using PRECLAV and HyperChem parameters.
Table VII. VIF values, Tolerance, Eigenvalue and Condition Number for the descriptors contained in the proposed models using PRECLAV descriptors for the set of 28 compounds.
Table VIII. VIF values, Tolerance, Eigenvalue and Condition Number for the best four - variable model for the set of 28 compounds using HyperChem parameters.
Table IX. Significant molecular virtual fragments for the Set of 28 compounds. Molecules of analyzed database include 32 virtual fragments. The mass percents of 4 fragments are significant. THE MOST SIGNIFICANT VIRTUAL FRAGMENTS by square correlation of ‘the mass percent of fragment' and ‘Property values' are