Calpain inhibitory flavonoids isolated from Orostachys japonicus

Figures & data

Table I.  Comparison of ¹³C-NMR data of compound 1 and herbacetin (solvent; DMSO-d₆).

C	Compound 1	Herbacetin [12]
2	147.2	145.0
3	136.1	135.5
4	176.3	176.3
5	156.5	152.4
6	98.8	98.2
7	157.4	152.9
8	124.4	124.8
9	148.7	146.7
10	103.2	102.9
1′	122.2	122.1
2′	130.2	129.8
3′	116.7	115.5
4′	159.6	159.3
5′	116.7	115.5
6′	130.2	129.8
1″	105.1
2″	72.1
3″	71.0
4″	66.7
5″	65.2

Figure 1.  Calpain inhibitory activity of subfractions (B1-B6, 100 μg/ml) of n-BuOH fraction.

Figure 2.  Structures of compounds 1-7 isolated from the B2 fraction of O. japonicus.

Figure 3.  Selected HMBC correlations of 1.

KR Markham, H Geiger. 1H nuclear magnetic resonance spectroscopy of flavonoids and their glycosides in hexadeuterodimethylsulfoxide. In: JB Harborne, editor. The flavonoids: Advances in Research Since 1986. London: Chapman & Hall; 1994. p 441–497.

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