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Research Article

Synthesis, spectroscopic, and antibacterial activity of tetraazamacrocyclic complexes of trivalent chromium, manganese, and iron

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Pages 1201-1206 | Received 10 Oct 2008, Accepted 21 Jan 2009, Published online: 23 Sep 2009

Figures & data

Figure 1. Synthesis of the complexes.

Figure 1.  Synthesis of the complexes.

Table 1. Analytical data for trivalent chromium, manganese, and iron complexes derived from succinyldihydrazide and benzil.

Figure 2. General structure of the complexes, where M = Cr(III), Mn(III), Fe(III), X = Cl, NO3, CH3COO for Cr(III) and Fe(III) and X = CH3COO for Mn(III).

Figure 2.  General structure of the complexes, where M = Cr(III), Mn(III), Fe(III), X = Cl−, NO3−, CH3COO− for Cr(III) and Fe(III) and X = CH3COO− for Mn(III).

Figure 3. Comparison of minimum inhibitory concentration (MIC) of complexes with those of standard antibiotics up to concentration of 64 μg/mL. a, Bacillus cereus (MTCC 1272); b, Staphylococcus aureus (MTCC 1144); c, Escherichia coli (MTCC 739); d, Salmonella typhi (MTCC 733); cefaclor and linezolid are standard antibiotics.

Figure 3.  Comparison of minimum inhibitory concentration (MIC) of complexes with those of standard antibiotics up to concentration of 64 μg/mL. a, Bacillus cereus (MTCC 1272); b, Staphylococcus aureus (MTCC 1144); c, Escherichia coli (MTCC 739); d, Salmonella typhi (MTCC 733); cefaclor and linezolid are standard antibiotics.

Table 2. Minimum inhibitory concentration (MIC) shown by complexes against test bacteria using agar dilution assay.

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