Figures & data
Table 1. Crystal data and structure refinement details for compounds 2–4.
Figure 2. An ORTEP drawing of asymmetric unit of 2 with the atom-numbering scheme. Displacement ellipsoids are drawn at the 40% probability level.
![Figure 2. An ORTEP drawing of asymmetric unit of 2 with the atom-numbering scheme. Displacement ellipsoids are drawn at the 40% probability level.](/cms/asset/c8b31ac4-0d09-45c2-a729-cf16ef0085d4/ienz_a_1247058_f0002_c.jpg)
Figure 3. An ORTEP drawing of asymmetric unit of 3 with the atom-numbering scheme. Displacement ellipsoids are drawn at the 40% probability level.
![Figure 3. An ORTEP drawing of asymmetric unit of 3 with the atom-numbering scheme. Displacement ellipsoids are drawn at the 40% probability level.](/cms/asset/de15aac1-9148-401a-9917-5b20e3b1a844/ienz_a_1247058_f0003_c.jpg)
Figure 4. An ORTEP drawing of asymmetric unit of 4 with the atom-numbering scheme. Displacement ellipsoids are drawn at the 40% probability level.
![Figure 4. An ORTEP drawing of asymmetric unit of 4 with the atom-numbering scheme. Displacement ellipsoids are drawn at the 40% probability level.](/cms/asset/a2d40d09-3c9d-450a-8110-3f3c21baf382/ienz_a_1247058_f0004_c.jpg)
Table 2. Selected bond distances [Å] and angles [°] of compounds 2–4.
Table 3. Hydrogen bonds for compounds 2–4 (Å, °).
Table 4. 1H-NMR and 13C-NMR chemical shifts (ppm) with coupling constants and assignments for compound 1.
Table 5. The inhibition data and Ki values of hCA I and hCA II isozymes for hydratase and esterase activity.