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Research Paper
Novel topoisomerase II/EGFR dual inhibitors: design, synthesis and docking studies of naphtho[2′,3′:4,5]thiazolo[3,2-a]pyrimidine hybrids as potential anticancer agents with apoptosis inducing activity
Mai A. E. Mourada Medicinal Chemistry Department, Faculty of Pharmacy, Port-Said University, Port-Said, EgyptCorrespondence[email protected]
https://orcid.org/0000-0002-9929-3741View further author information
, https://orcid.org/0000-0002-9929-3741View further author information
Ayman Abo Elmaatya Medicinal Chemistry Department, Faculty of Pharmacy, Port-Said University, Port-Said, EgyptView further author information
, Islam Zakib Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Port-Said University, Port-Said, EgyptView further author information
, Ahmed A. E. Mouradc Pharmacology and Toxicology Department, Faculty of Pharmacy, Port-Said University, Port-Said, Egypthttps://orcid.org/0000-0001-8823-8774View further author information
, Amal Hofnid Department of Pharmacology and Toxicology, Faculty of Pharmacy, South Valley University, Qena, EgyptView further author information
, Ahmed E. Khodire Department of Pharmacology, Faculty of Pharmacy, Horus University, New Damietta, EgyptView further author information
, Esam M. Aboubakrd Department of Pharmacology and Toxicology, Faculty of Pharmacy, South Valley University, Qena, EgyptView further author information
, Ahmed Elkamhawyf BK21 FOUR Team and Integrated Research Institute for Drug Development, College of Pharmacy, Dongguk University—Seoul, Goyang, Republic of Korea;g Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, EgyptView further author information
, Eun Joo Rohh Chemical and Biological Integrative Research Center, Korea Institute of Science and Technology (KIST), Seoul, Korea;i Division of Bio-Medical Science & Technology, University of Science and Technology, Daejeon, KoreaCorrespondence[email protected]
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& View further author information
Ahmed A. Al-Karmalawyj Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ahram Canadian University, 6th of October City, Giza, Egypthttps://orcid.org/0000-0002-8173-6073View further author information
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Article: 2205043
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Received 13 Mar 2023, Accepted 16 Apr 2023, Published online: 11 May 2023
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