Early-onset preeclampsia is associated with perinatal mortality and severe neonatal morbidity

Figures & data

Table 1. Perinatal outcome.

	PE neonates	Non-PE neonates
	N = 97	N = 680	p values
Gestational age at delivery (weeks)	30 [25–36]	30 [25–36]	0.89
Male gender	41 (43)	344 (51)	0.18
Female gender	56 (57)	336 (49)	0.18
1 min Apgars score	7 [1–10]	7 [0–10]	0.30
5 min Apgars score	9 [0–10]	8 [0–10]	0.015
Birth weight (grams)	1150 [400–2710]	1430 [480–4147]	0.001
SGA (<p10)	21 (22)	58 (9)	0.001
Cesarean section	64 (66)	226 (34)	0.001
Perinatal mortality	13 (13)	48 (7)	0.03
Infant mortality	15 (16)	58 (9)	0.03

Data are number of patients (%) or median [range].

p values of <0.05 was considered significant and indicated in italic font.

Figure 1. Perinatal mortality rate among PE vs. non-PE neonates according to SGA subgroup analysis.

Table 2. Neonatal complications.

	PE neonates	Non-PE neonates
	N = 97	N = 680	p values
IRDS^a	56 (62)	342 (50)	0.045
Surfactant treatment^a	45 (50)	226 (33)	0.002
Pneumothorax^a	3 (3)	17 (3)	0.67
Sepsis^a	41 (43)	204 (30)	0.01
Intracranial hemorrhage^a			0.77
grade I	13 (14)	103 (15)
grade II	1 (1)	13 (2)
grade III–IV	0 (0)	0 (0)
Periventricular leukomalacia^a			0.50
grade I	11 (12)	96 (14)
grade II–IV	0 (0)	0 (0)
Retinopathy^a			0.66
grade I	5 (6)	26 (4)
grade II	0 (0)	2 (0.3)
grade III–V	0 (0)	0 (0)
Necrotizing enterocolitis^a			0.92
stage I–III	9 (9)	61 (9)

Data are number of patients (%).

^a Some patients match more than one complication.

Some data (N = 7) are missing.