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Original Article

Placental ghrelin and leptin expression and cord blood ghrelin, adiponectin, leptin, and C-peptide levels in severe maternal obesity

, & ORCID Icon
Pages 2839-2846 | Received 10 Feb 2017, Accepted 18 Jul 2017, Published online: 08 Aug 2017

Figures & data

Table 1. Clinical characteristics of obese and normal-weight women and their offspring.

Figure 1. Mean weight z-scores ± SEM from birth until 48 months of age in children born to obese (OB) and normal-weight (NW) mothers.

Figure 1. Mean weight z-scores ± SEM from birth until 48 months of age in children born to obese (OB) and normal-weight (NW) mothers.

Figure 2. Box plots of ghrelin, adiponectin, leptin, and C-peptide concentrations in cord blood from children born to obese and normal-weight women. The boxes represent the interquartile range, the horizontal bars are the median, and whiskers are the range. *The leptin and the C-peptide concentrations were significantly higher in infants born to obese mothers (p = .016 and p = .027, respectively). OB: obese mother; NW: normal-weight mother.

Figure 2. Box plots of ghrelin, adiponectin, leptin, and C-peptide concentrations in cord blood from children born to obese and normal-weight women. The boxes represent the interquartile range, the horizontal bars are the median, and whiskers are the range. *The leptin and the C-peptide concentrations were significantly higher in infants born to obese mothers (p = .016 and p = .027, respectively). OB: obese mother; NW: normal-weight mother.