Should all diabetic patients take statin therapy regardless of serum cholesterol level?

Figures & data

Table 1. Statin therapy recommendation based on ASCVD risk score[7].

DM with ASCVD Risk Calculator (%)	Age (Years)	Recommended statin intensity and combination treatment (In addition to lifestyle therapy).
<7.5%	<40	None (only lifestyle therapy).
	40–75	Moderate dose statin^⋆
≥7.5%	40–75	High dose statin.

⋆Moderate-intensity statin may be considered based on LDL-C > 70 mg/dl.

DM – diabetes mellitus; ASCVD – atherosclerosis cardiovascular disease.

Table 2. Statin therapy recommendation in diabetic patient based on ASCVD score and LDL serum level [7].

LDL-C Level (mg/dl)	<70 mg/dl	>70 mg/dl	<70 mg/dl
ASCVD Risk Calculator (%)	<7.5%	<7.5%	≥7.5%
Age (years)	Any Age	40–75	40–75
Statin Therapy	None	Moderate Intensity Statin	High Intensity Statin

ASCVD – atherosclerosis cardiovascular disease; LDL-C – low-density lipoprotein – cholesterol.

care ADAJD. 9. Cardiovascular disease and risk management: standards of medical care in diabetes—2018. Diabetes Care. 2018;41(Supplement 1):S86–S104.

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