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Natural Product Research
Formerly Natural Product Letters
Volume 18, 2004 - Issue 5
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Original Articles

Paludolactone: A new Eudesmanolide Lactone from Wedelia Paludosa Dc. (Acmela Brasiliensis)

Valdir Cechinel Filho Núcleo de Investigações Químico-Farmacêuticas (NIQFAR), CCS, Universidade do Vale do Itajaí (UNIVALI), 88302-202, Itajaí, SC, Brazil
,
Luciana C. Block Núcleo de Investigações Químico-Farmacêuticas (NIQFAR), CCS, Universidade do Vale do Itajaí (UNIVALI), 88302-202, Itajaí, SC, Brazil
,
Rosendo A. Yunes Departamento de Química, Universidade Federal de Santa Catarina (UFSC), 88040-900, Florianópolis, SC, Brazil
&
Franco Delle Monache Centro Chimica Recettori, CNR, 00168, Rome, Italy
Pages 447-451 | Received 12 Jun 2003, Accepted 18 Oct 2003, Published online: 21 Aug 2006
 
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Abstract

Phytochemical investigation of the whole plant of Wedelia paludosa (Acmela brasiliensis) furnished a new eudesmanolide lactone, named paludolactone (2), in addition to the known eudesmanolide (1), stigmasterol, kaurenoic and oleanolic acids. 1H- and 13C-NMR, and MS spectroscopic and elemental analyses were used for the structural elucidation of these compounds.

Acknowledgment

The authors are grateful to CNPq (Brazil) for financial support.

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