Iridoid and lignan glycosides from Citharexylum spinosum L.

Abstract

From the aerial parts of Citharexylum spinosum L., one new iridoid glucoside, the 7-β-O-acetate (1) of lamiide, along with four known iridoid glucosides, lamiide (2), lamiidoside (3), duranterectoside C (4), 8-epiloganin (5) and one known lignan glucoside (+)-lyonirenisol-3a-O-β-D-glucopyranoside (6) were isolated. The compound structures were established by one- and two-dimensional ¹H- and ¹³C-NMR as well as by ESI-MS spectra.

Keywords:

• Citharexylum spinosum L.
• Iridoid glucoside
• Lamiide-7-β-O-acetate
• Lignan glucoside

Acknowledgements

This work was supported by the Hungarian Academy of Sciences (Project MTA/DFG 2002–2004), by the Hungarian National Research Foundation (OTKA No. T046127) and by the Deutsche Forschungsgemeinschaft. This work has been performed within the project “Biologically Active Natural Products, Synthetic Diversity” (Department of Chemistry, Hannover University). H.S.M. Soliman thanks Prof. Dr. K. Seifert, Institute of Organic Chemistry, Bayreuth University, Germany, for allowing use of laboratory facilities.