Mutagenic, antimutagenic and antioxidant activities of a new polyphenolic and a flavonoid substances isolated from Anagallis monelli

Abstract

A new polyphenolic natural substance: 2,5-dihydroxy-benzoic acid 3′-formyl-5′-hydroxy-phenyl ester (1), Anamighrinal and 3-(O-α-L-rhamnosyl) quercetin (2) have been isolated from the methanolic aerial part extract of the plant Anagallis monelli by chromatographic separation. Their structures have been deduced essentially by one and two NMR spectroscopic procedures and mass spectrometry. Antioxidant, mutagenic, antimutagenic activities, of the natural products were realised and positive results were recorded.

Keywords:

• Anagallis monelli
• NMR
• New substance
• Antioxidant
• Mutagenic
• Antimutagenic

Acknowledgements

The authors wish to thank Dr F. Harzallah-Skhiri, laboratoire de Biologie végétale, Institut Supérieur de Biotechnologie, Monastir, Tunisia, for botanical classification of the plant material.