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Natural Product Research
Formerly Natural Product Letters
Volume 22, 2008 - Issue 14
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Original Articles

Two new bioactive oleanane triterpene glycosides from Terminalia arjuna

, , , , &
Pages 1279-1288 | Received 22 Apr 2006, Accepted 18 Aug 2006, Published online: 27 Jul 2010
 

Abstract

Two new oleanane-type triterpene glycosides designated as Termiarjunoside I and Termiarjunoside II were isolated from stem bark of Terminalia arjuna (Combretaceae) and characterized as olean-1α,3β,9α,22α-tetraol-12-en-28-oic acid-3β-D-glucopyranoside (1) and olean-3α,5α,25-triol-12-en-23,28-dioic acid-3α-D-glucopyranoside (2) based on chemical and spectral data evidences. Both compounds 1 and 2 potently suppressed the release of nitric oxide and superoxide from macrophages and also inhibited aggregation of platelets.

Acknowledgement

Council of Scientific and Industrial Research (CSIR) is acknowledged for providing the financial assistance to one of us (GK).

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