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Natural Product Research
Formerly Natural Product Letters
Volume 24, 2010 - Issue 2
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Original Articles

A novel lupene-type triterpenic glucoside from the leaves of Clerodendrum inerme

, , &
Pages 167-176 | Received 13 Jan 2009, Accepted 10 Apr 2009, Published online: 13 Jan 2010
 

Abstract

A new triterpenic glucoside, lup-1,5,20(29)-trien-3-O-β-D-glucopyranoside (4), along with three known phytoconstituents: n-octacosane, friedelin and β-amyrin, has been isolated from the leaves of Clerodendrum inerme (L.) Gaertn. (Verbenaceae). Structure elucidation was carried out on the basis of chemical and physical evidence (IR, 1H-NMR, 13C-NMR, DEPT and MS spectra). The alcoholic and aqueous extracts of the leaves of C. inerme showed significant antinociceptive activity in analgaesiometer tests.

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