A new chromene from the fruiting bodies of Chroogomphus rutilus

Abstract

A new chromene, acetic acid 2R-(4,8-dimethylnona-3,7-dienyl)-8-hydroxy-2-methyl-2H-chromen-6-yl ester (1), was isolated from the fruiting bodies of Chroogomphus rutilus, together with six known compounds (2–7). The structures of these compounds were identified based on 1D and 2D NMR, including ¹H–¹H COSY, HMQC and HMBC spectroscopic methods. Of these seven compounds, 2 and 3 showed cytotoxicity against HSC-T6, SK-Hep1 and A549 cell lines.

Keywords::

• Chroogomphus rutilus
• Gomphidiaceae
• cytotoxicity

Acknowledgements

This work was supported by the National Natural Science Foundation of China [grant number 81160386], [grant number 81260474].

Notes

^1. These authors contributed equally to the work.