Advanced search
Publication Cover
Natural Product Research
Formerly Natural Product Letters
Volume 30, 2016 - Issue 11
Submit an article Journal homepage
311
Views
22
CrossRef citations to date
0
Altmetric
Articles

New cytotoxic constituents from the Red Sea soft coral Nephthea sp.

Mohamed-Elamir F. HegazyPhytochemistry Department and Center of Excellence for Advanced Sciences, National Research Centre, 33 El Bohouth st. (Former El Tahrir st.) Dokki, Giza, P.O. Box 12622, EgyptCorrespondence[email protected]
View further author information
,
Amira M. Gamal-EldeenCancer Biology Lab, Center of Excellence for Advanced Sciences, and Biochemistry Department, National Research Centre, 33 El Bohouth st. (Former El Tahrir st.) Dokki, Giza, P.O. Box 12622, EgyptView further author information
,
Tarik A. MohamedPhytochemistry Department and Center of Excellence for Advanced Sciences, National Research Centre, 33 El Bohouth st. (Former El Tahrir st.) Dokki, Giza, P.O. Box 12622, EgyptView further author information
,
Montaser A. AlhammadyNational Institute of Oceanography and Fisheries, Red Sea Branch, Hurghada84511, EgyptView further author information
,
Abuzeid A. HassanienDepartment of Chemistry, Faculty of Science, Suez University, EgyptView further author information
,
Mohamed A. ShreadahNational Institute of Oceanography & Fisheries, Alexandria, EgyptView further author information
,
Ibrahim I. AbdelgawadDepartment of Chemistry, Faculty of Science, Suez University, EgyptView further author information
,
Eman M. ElkadyNational Institute of Oceanography & Fisheries, Alexandria, EgyptView further author information
&
Paul W. ParéDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX79409, USAView further author information
 show all
Pages 1266-1272 | Received 20 Mar 2015, Accepted 20 May 2015, Published online: 13 Jul 2015
 
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Abstract

Nephthea are soft coral species rich in sesquiterpenoids and steroids. An organic extract of Nephthea sp. resulted in the isolation of a new steroid (1), as well as several previously reported metabolites (2–9). Structures were elucidated by employing NMR and HR-EI-MS analyses. The total extract, fractions and purified compounds exhibited differential cytotoxicity against the breast cancer MCF-7 cell line.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This project was supported financially by the Science and Technology Development Fund (STDF), Egypt [grant number 1102].

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 61.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 861.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.