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Abstract
Two new diacetylene glycosides: bhutkesoside A (1) and B (2), along with 10 known compounds, i.e. falcarindiol (3), chlorogenic acid (4), 5-O-p-coumaroyl-quinic acid (5), 3,5-di-O-caffeoyl-quinic acid (6), 4-hydroxy-7-methoxy-phenylethanol (7), ferulic acid (8), dehydrodiconiferyl alcohol-4-O-β-d-glucopyranoside (9), 5,7-dihydroxy-2-methylchromone-7-O-rutinoside (10), schumanniofioside B (11) and marmesinin (12) were isolated from the roots of Ligusticopsis wallichiana (DC) Pimenov & Kljuykov (Apiaceae), commonly known as ‘Bhutkesh’ in Nepal. The structures were determined on the basis of spectroscopic data. Compounds 4 and 6 showed potent antioxidant activity on DPPH free radical scavenging assay.
Acknowledgements
The authors are grateful to the Program for Leading Graduate Schools ‘HIGO Program’ (Health life science: Interdisciplinary and Glocal Oriented), MEXT, Japan for scholarship to Mr Bibek Adhikari. We are grateful to Ms Teruo Tanaka and Mr Toshiyuki Iriguchi of Institute of Resource Development and Analysis, Kumamoto University for measurement of NMR and mass spectra, respectively.
Disclosure statement
No potential conflict of interest was reported by the authors.