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Natural Product Research
Formerly Natural Product Letters
Volume 31, 2017 - Issue 16
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Research Articles

Secondary metabolites from Colletotrichum capsici, an endophytic fungus derived from Siegesbeckia pubescens Makino

Fuqian WangDepartment of Pharmacy, Wuhan First Hospital, Wuhan, China
,
Haoran MaDepartment of Pharmacy, Wuhan First Hospital, Wuhan, China
,
Zhengxi HuHubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
,
Jie JiangDepartment of Pharmacy, Wuhan First Hospital, Wuhan, China
,
Hucheng ZhuHubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
,
Lu ChengDepartment of Pharmacy, Wuhan First Hospital, Wuhan, China
,
Quanwei YangDepartment of Pharmacy, Wuhan First Hospital, Wuhan, China
,
Hong ZhangDepartment of Pharmacy, Wuhan First Hospital, Wuhan, ChinaCorrespondence[email protected]
,
Geng ZhangDepartment of Pharmacy, Wuhan First Hospital, Wuhan, ChinaCorrespondence[email protected]
&
Yonghui ZhangHubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaCorrespondence[email protected]
 show all
Pages 1849-1854 | Received 03 Sep 2016, Accepted 01 Nov 2016, Published online: 28 Nov 2016
 
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Abstract

A rare new tremulane sesquiterpenoid analogue, 11,12-epoxy-5,6-seco-1,6(13)-tremuladien-5,12-olide (1), together with five known altenuene derivatives (2–6) was isolated from the cultures of Colletotrichum capsici, which was isolated as an endophytic fungus from fresh leaves of Siegesbeckia pubescens Makino (Compositae). Their structures were elucidated by means of spectroscopic methods and comparison with literature data. All compounds isolated were reported for the first time from the fungus C. capsici.

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