3″-Hydroxymethyl-butyrolactone II from Aspergillus sp

Abstract

In continuation of the search for new compounds from the terrestrial fungus Aspergillus sp., one new butyrolactone, 3″-hydroxymethyl-butyrolactone II (1) was isolated. The chemical structure of 1 was confirmed by extensive 1D and 2D NMR and HR-ESI mass data analysis, and by comparison with literature data. The absolute configuration was also determined by ECD calculations.

Graphical Abstract

KEYWORDS:

• Aspergillus sp.
• 3″-hydroxymethyl-butyrolactone II
• structure elucidation
• biological activity

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This research project was financed by Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology (LMDBKF201701); National Natural Science Foundation of China (No. 81202425).