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Natural Product Research
Formerly Natural Product Letters
Volume 35, 2021 - Issue 20
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Research Articles

A new cycloartane triterpene bisdesmoside from the rhizomes of Actaea vaginata

Minli Zhanga College of Medicine, Xi'an International University, Xi’an, P.R. China;c Faculty of Medicine and Health Sciences, University Malaysia Sabah, Kota Kinabalu, MalaysiaView further author information
,
Qinwen Yangb Beijing Key Laboratory of New Drug Discovery based on Classic Chinese Medicine Prescription, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. ChinaView further author information
,
Xiaofeng Zhanga College of Medicine, Xi'an International University, Xi’an, P.R. China;c Faculty of Medicine and Health Sciences, University Malaysia Sabah, Kota Kinabalu, MalaysiaView further author information
&
Haifeng Wub Beijing Key Laboratory of New Drug Discovery based on Classic Chinese Medicine Prescription, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. ChinaCorrespondence[email protected]
View further author information
Pages 3426-3431 | Received 24 Oct 2019, Accepted 01 Dec 2019, Published online: 10 Dec 2019
 
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Abstract

A new cycloartane triterpene bisdesmoside, soulieoside T (1), and one known compound, oleanolic acid (2), were isolated from the ethanolic extract of the rhizomes of Actaea vaginata. Their structures were elucidated by spectroscopic methods and by comparison with data reported in the literature. Compound 1 was evaluated for cytotoxic activities against three human cancer cell lines.

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Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was financially supported from the CAMS Innovation Fund for Medical Sciences (CIFS, No. 2019-I2M-1-005, 2017-I2M-1-013), Huai’an 2017 Annual Promotion Project for Science and Technology International Cooperation (HAC201702) and the State Scholarship Fund from China Scholarship Council.

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