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Abstract
Four new triterpene glucosides (1–4) were isolated from the 90% ethanol extract of Salacia cochinchinensis, together with five known compounds (5–9). The structures of the new compounds were elucidated by comprehensive spectroscopic analysis including HRESIMS, IR, 1 D and 2 D NMR analysis. All isolates were assayed for their α-glucosidase inhibitory activity. Compound 9 showed remarkable α-glucosidase inhibitory activity with an IC50 value of 0.31 μM, and the triterpene glycosides (1–5) exhibited moderate α-glucosidase inhibitory activity.
Graphical Abstract
Disclosure statement
No potential conflict of interest was reported by the author(s).
Additional information
Funding
This work was financially supported by the National Natural Science Foundation of China (NSFC No. 81560708, 81860620), the Biodiversity Investigation, Observation and Assessment Program of Ministry of Ecology and Environment of China (2019–2023), the Natural Science Foundation of Jiangsu Province, China (No. BK20160103), and the Reserve Talent Project of Middle & Young Academic Leaders in Yunnan Province (2015HB050, 2019Y0206). The authors appreciated the staff of the analytical group from the State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, for the measurements of all spectra.