Phytochemicals from twigs of Afzelia xylocarpa and their antioxidation kinetics of oxymyoglobin

Abstract

The phytochemical investigation of crude n-hexane and ethyl acetate extracts from twigs of Afzelia xylocarpa (Kurz) led to the isolation of 14 known compounds. Their structures were elucidated by spectroscopic techniques (IR, ¹H NMR, ¹³C NMR, and 2D NMR) as well as mass spectrometry. These structures were characterized as β-sitosterol (1), lupeol (2), vanilic acid (3), 5,7-dihydroxychromone (4), (+)-mellein (5), isoliquiritigenin (6), 7-hydroxyemodin (7), physion (8), aromadendrin (9), naringenin (10), apigenin (11), luteolin (12), chrysoeriol (13) and kaempferol (14). Compounds 4–7 and 12–13 were isolated from the genus Afzelia for the first time. The selected compounds 5, 8, 9 and 12 exhibited potent activity for antioxidation kinetics of oxymyoglobin.

Graphical Abstract

Keywords:

• Afzelia xylocarpa
• anthraquinone
• flavanone
• flavonone
• oxymyoglobin

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

The Thailand Research Fund (Grant No. DBG5980001), the Faculty of Science, Mahasarakham University, Thailand, the Research Instrument Center, Khon Kaen University, Thailand, the Center of Excellence for Innovation in Chemistry (PERCH-CIC), Office of the Higher Education Commission, Ministry of Education, Thailand are acknowledged for financial supports. We thank Assoc. Prof. Dr. Surapon Saensouk, Mahasarakham University Herbarium, Thailand, for plant identification.