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Natural Product Research
Formerly Natural Product Letters
Volume 36, 2022 - Issue 20
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Research Articles

Acroflavone A, a new prenylated flavone from the fruit of Acronychia pedunculata (L.) Miq

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Pages 5330-5336 | Received 07 May 2021, Accepted 29 May 2021, Published online: 15 Jun 2021
 

Abstract

Phytochemical investigation of the fruit of Acronychia pedunculata (L.) Miq. led to the isolation of a new prenylated flavone, acroflavone A (1), together with eight known compounds (29). Their structures were elucidated by thorough analysis of mass spectrometric and NMR spectroscopic data. The isolated compounds were evaluated against several bacterial strains. Three known compounds (35) demonstrated antibacterial activities. Among them, acrovestone (5) proved equally or more potent than chloramphenicol against three out of the four strains tested.

GRAPHICAL ABSTRACT

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was supported by the Center of Excellence for Innovation in Chemistry (PERCH-CIC) and Khon Kaen University. This project was funded by the National Research Council of Thailand (NRCT) contract n° NRCT5-TRG63003-01. A.W. thanks the Science Achievement Scholarship of Thailand (SAST) for a scholarship.

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