Abstract
Sixteen compounds (1-16) were isolated from Impatiens chapaensis. Chemical structures were determined by spectroscopic analyses and comparisons with previously published data. This report is the first to identify compounds 1, 5–7, 10, 12–14, and 16 from the genus Impatiens. Seven chosen isolates (5, 7, 10, 11, 12, 15, and 16) were submitted for α-glucosidase inhibition assays with acarbose as the positive control (IC50 = 227.14 ± 13.71 µM). Flavonoid 5 exhibited a significant inhibitory effect (IC50 = 101.00 ± 9.01 µM).
Graphical Abstract
Disclosure statement
No conflict of interest was reported by the authors.
Supplementary material
Supporting material relating to this article is available online: detailed experimental section; NMR spectroscopic data; NMR spectra of compounds 1–16; CD spectra of 1, 2, 5 and 16; nitric oxide (NO) inhibition and α-glucosidase inhibition assays; and biological data.
Correction Statement
This article has been republished with minor changes. These changes do not impact the academic content of the article.