https://orcid.org/0000-0002-5235-739X
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Abstract
Two new alkaloids designated aspernigrin E (1) and pyranonigrin L (2) were isolated from mangrove endophytic fungus Aspergillus fumigatus SAS10, together with the known alkaloid compounds pyranonigrin A (3), asperazine (4), (+)-iso-pestalazine A (5), pestalazine A (6), and pestalazine B (7). The planar structures of the new compounds were elucidated by HR-MS and NMR spectroscopic data analyses. The absolute configurations of compounds 1 and 2 were determined by comparison of the electronic circular dichroic (ECD) spectra with the calculated ECD spectra. All these compounds were tested for anti-bacterial activity.
Graphical Abstract
Disclosure statement
No potential conflict of interest was reported by the author(s).
Additional information
Funding
This study was supported in part by Guangdong Natural Science Foundation [2023A1515010968], National Natural Science Foundation of China [21977103], Guangzhou Education Bureau Project for Yangcheng Scholars [202032774], Undergraduates’ Improving Programs of Scientific Research and Innovation Ability in Guangzhou Medical University [02-408-2203-2026], and the Undergraduate Teaching Quality and Teaching Reform Project Construction Project of Guangdong Province in 2022-“Guangzhou Medical University and Xinbaotang Company” Practice Teaching Base for Integrating Science, Industry, and Education [YJGH (2023) No.4].