Preparation and antifungal activity evaluation of hinokitiol emulsifiable concentrate against Sclerotinia sclerotiorum

Abstract

Hinokitiol is a natural broad-spectrum antimicrobial monoterpenoid, which is widely used as an antiseptic in food, cosmetics and other products. In the present study, the toxic actions of hinokitiol to the plant pathogen Sclerotinia sclerotiorum were investigated. The EC₅₀ value for mycelial growth inhibition was 2.63 μg/mL, and there was no positive or negative cross-resistance between hinokitiol and carbendazim. The emulsifiable concentrate of 30% hinokitiol was prepared, which has excellent application prospect in the prevention of sclerotinia and gray mould. Hinokitiol is a promising spray fungicide for stems and leaves rather than seeds and roots.

Graphical Abstract

Keywords:

• Hinokitiol
• Sclerotinia sclerotiorum
• antifungal activity
• emulsifiable concentrate

Acknowledgements

Thanks to Professor Yingqian Liu for providing research materials.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

Supported by the Key Research and Development Program of Gansu Academy of Agricultural Sciences (2022GAAS29); National Key R&D Program of China (2023YFD2302100).