https://orcid.org/0000-0002-5198-8827
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ABSTRACT
The aim of the study is to investigate the inflammation markers in bipolar affective disorder(BAD) patients who were involved in crime or did not involve in crime. It was aimed to evaluate the neutrophil/lymphocyte ratios (NLR), platelet/lymphocyte ratios (PLR), monocyte/lymphocyte ratios (MLR) and platelete distribution width (RDW) by comparing with controls and each other. 272 individuals were included in our study; patients diagnosed with BAD (100 committed a crime, 72 has no criminal history) in the patient group and 100 individuals in the control. The hemoglobin, hematocrit and PDW levels were found higher in the group involved in crime than the group not involved in crime as well as controls. Also, hemoglobin, hematocrit, WBC, RBC, PDW, neutrophil, monocyte values were found higher in the patients involved in crime than the patients not involved in crime. NLR, PLR and MLR were found low in both patient groups compared to controls. Based on our results; some inflammatory parameters were different in the patients involved in crime than the group not involved in crime and healthy controls. To generalize the findings of our study and to make them significant, prospective studies should be conducted with larger sample groups and people with different disorders.
Acknowledgments
No financial support.
Ethics committee approval
The study was conducted following the Helsinki Declaration after obtaining approval from Gaziosmanpaşa University, Non-Interventional Local Ethics Committee (with project number 20-KAEK-148).
Disclosure statement
No conflict of interest was declared by the authors.
Financial disclosure
The authors declared that this study received no financial support.
Informed consent
Retrospective study.