Synthesis and Characterization of Some New N-Glycosides of Pyridine-2,6-bis-Carboxamides Derivatives

ABSTRACT

A series of novel pyridine-bridged 2,6-bis-carboxamide N-β-glycosides and Schiff's bases has been prepared starting from 2,6-bis-carboxamide pyridine hydrazide, which on treatment with appropriate monosaccharides, aromatic or heterocyclic aldehydes, and indoline-2,3-dione derivatives afforded the corresponding sugar hydrazones and pyridine-bridged 2,6-bis-carboxamide Schiff's bases.

KEYWORDS:

• Pyridine-2,6-carboxamides
• Schiff's bases
• N-glycosides

Funding

The project was financially supported by Vice Deanship of Research Chairs, King Saud University, Riyadh, Saudi Arabia.