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ABSTRACT
This study determined the association between fine particles (PM2.5) levels and hospital admissions for chest pain (CP) in Taipei, Taiwan. Hospital admissions for CP and ambient air pollution data for Taipei were obtained for the period 2009–2013. The relative risk of hospital admissions was estimated using a case-crossover approach, after controlling for weather variables, day of the week, seasonality, and long-term time trends. For single-pollutant models (without adjustment for other pollutants), increased frequency of CP admissions was significantly associated with PM2.5 levels on warm days (>23°C), with an interquartile range rise correlated with a 15% (95% confidence interval = 11–31%) elevation in number of CP admissions. In two-pollutant models, PM2.5 remained significant after inclusion of each of the other four pollutants: sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), and ozone (O3) on warm days. Generally, no marked associations were observed between PM2.5 levels and risk of CP admissions on cool days in both single- and two-pollutant models. This study provides evidence that higher PM2.5 concentrations enhance the risk of hospital admissions for CP on warm days.
Funding
This study is based in part on data from the National Insurance Research Database provided by the Bureau of National Health Insurance (BNHI), Ministry of Health and Welfare (MOHW) and managed by National Health Research Institutes (NHRI). The interpretation and conclusions contained herein do not represent those of BNHI, MOHW, or NHRI. This study was supported by grants from NHRI, Taiwan (06A1-EMPP08-014) and Ministry of Science and Technology, Executive Yuan, Taiwan (MOST 104-2314-B-037-015-MY3).