576
Views
5
CrossRef citations to date
0
Altmetric
Bedside to Bench Report

Isolated cardiac peripheral primitive neuroectodermal tumor: A case report

, , &
Pages 4-7 | Received 08 Sep 2016, Accepted 20 Nov 2016, Published online: 03 Jan 2017

Figures & data

Figure 1. (A) Four chamber view of CT showing a hypo-intense tumorous mass extending from the left ventricle with the coronary artery infiltrating (arrow). FDG PET-CT shows a high uptake lesion (40 mm × 30 mm) located in the posterior-inferior of the left ventricle (arrows in B, (C) and D) with severe focal FDG activity (SUV max 9.0).

Figure 1. (A) Four chamber view of CT showing a hypo-intense tumorous mass extending from the left ventricle with the coronary artery infiltrating (arrow). FDG PET-CT shows a high uptake lesion (40 mm × 30 mm) located in the posterior-inferior of the left ventricle (arrows in B, (C) and D) with severe focal FDG activity (SUV max 9.0).

Figure 2. Surgical exploration reveals a firm 40 mm × 30 mm × 30 mm mass with coronary infiltrated.

Figure 2. Surgical exploration reveals a firm 40 mm × 30 mm × 30 mm mass with coronary infiltrated.

Figure 3. Post-operative histological examination showing small cell malignant tumor and highly suspicious of malignant peripheral primitive neuroectodermal tumor with CD99 and NSE intense positive identification. Magnification, A: x100, B: x200.

Figure 3. Post-operative histological examination showing small cell malignant tumor and highly suspicious of malignant peripheral primitive neuroectodermal tumor with CD99 and NSE intense positive identification. Magnification, A: x100, B: x200.

Figure 4. MAP kinase pathways and their mammalian ETS-domain transcription factor targets. ERK, p38 and JNK pathways are activated by distinct upstream kinases in response to a wide variety of extracellular signals such as growth factors, cytokine factors, and stress. Various substrates in the cytoplasma and the nucleus of the cell were activated, including transcription factors. These downstream targets control cellular responses.

Figure 4. MAP kinase pathways and their mammalian ETS-domain transcription factor targets. ERK, p38 and JNK pathways are activated by distinct upstream kinases in response to a wide variety of extracellular signals such as growth factors, cytokine factors, and stress. Various substrates in the cytoplasma and the nucleus of the cell were activated, including transcription factors. These downstream targets control cellular responses.
Supplemental material

Supplementarymaterials.zip

Download Zip (2.7 MB)

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.