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Bedside-to-Bench Report

Ototoxicity in patients with invasive ductal breast cancer who were treated with docetaxel: report of two cases

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Pages 990-993 | Received 14 Jan 2019, Accepted 15 Sep 2020, Published online: 29 Oct 2020

Figures & data

Figure 1. (a) Postoperative pathology revealed invasive ductal carcinoma (HE, 100× magnification). (b) Immunohistochemical staining of the resected specimen showed ER (1+), PR (-), HER-2 (2+), fish (-), Ki-67(20%~30%). Postoperative pathology revealed invasive ductal carcinoma (HE, 100× magnification). Immunohistochemistry showed ER (-), PR (-), HER-2 (-), Ki-67(50%)

Figure 1. (a) Postoperative pathology revealed invasive ductal carcinoma (HE, 100× magnification). (b) Immunohistochemical staining of the resected specimen showed ER (1+), PR (-), HER-2 (2+), fish (-), Ki-67(20%~30%). Postoperative pathology revealed invasive ductal carcinoma (HE, 100× magnification). Immunohistochemistry showed ER (-), PR (-), HER-2 (-), Ki-67(50%)

Figure 2. Pure tone audiometry showed bilateral sensorineural hearing loss. Figure A, B, C and D showed the pure tone audiometry performed by the patient on December 11, 2017, December 25, 2017, January 9, 2018 and March 30, 2018 respectively. Blue for left ear and red for right ear. The range of pure-tone in normal people is between 0 dB and 25 dB. The patient’s bilateral ears had pure-tone averages of greater than 70 dB for air conduction (125 to 8000 Hz), which was classified as severe hearing loss according to the WHO classification criteria

Figure 2. Pure tone audiometry showed bilateral sensorineural hearing loss. Figure A, B, C and D showed the pure tone audiometry performed by the patient on December 11, 2017, December 25, 2017, January 9, 2018 and March 30, 2018 respectively. Blue for left ear and red for right ear. The range of pure-tone in normal people is between 0 dB and 25 dB. The patient’s bilateral ears had pure-tone averages of greater than 70 dB for air conduction (125 to 8000 Hz), which was classified as severe hearing loss according to the WHO classification criteria