Figures & data
Figure 1. Regulation of DAXX phosphorylation by the ATM/Wip1 Axis. ATM protein kinase and Wip1 protein phosphatase promote (green arrows) or reduce (red arrows) phosphorylation of p53 and DAXX, respectively. Notice the negative feedback loop linking p53 to Wip1 (yellow arrow) and by which p53 is autoregulated.
![Figure 1. Regulation of DAXX phosphorylation by the ATM/Wip1 Axis. ATM protein kinase and Wip1 protein phosphatase promote (green arrows) or reduce (red arrows) phosphorylation of p53 and DAXX, respectively. Notice the negative feedback loop linking p53 to Wip1 (yellow arrow) and by which p53 is autoregulated.](/cms/asset/12664e94-6d01-49e8-9b39-f06750907b91/kccy_a_1006552_f0001_c.gif)