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Cell Cycle Volume 14, 2015 - Issue 6
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Editorials: Cell Cycle Features

Myheart hits the core of chromatin

Pei HanKrannert Institute of Cardiology and Division of Cardiology; Department of Medicine;Division of Cardiovascular Medicine; Stanford University School of Medicine; Stanford, CAUSA
&
Ching-Pin ChangKrannert Institute of Cardiology and Division of Cardiology; Department of Medicine;Department of Biochemistry and Molecular Biology; Indiana University School of Medicine; Indianapolis, INUSA;Department of Medical and Molecular Genetics; Indiana University School of Medicine; Indianapolis, INUSACorrespondence[email protected]
Pages 787-788 | Received 05 Jan 2015, Accepted 16 Jan 2015, Published online: 19 Mar 2015

Figures & data

Figure 1. Brg1 (orange) recognizes and binds to the chromatinized/nucleosomal DNA, which wraps around the histone core (left panel). The long noncoding RNA Myheart (emerald) binds to Brg1 and sequesters it from its genomic DNA target locus (right panel).

Figure 1. Brg1 (orange) recognizes and binds to the chromatinized/nucleosomal DNA, which wraps around the histone core (left panel). The long noncoding RNA Myheart (emerald) binds to Brg1 and sequesters it from its genomic DNA target locus (right panel).

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