Figure 1. Potential functional and sterilizing cures of HIV by CRISPR/Cas9-mediated gene editing in human stem cells. CIRSPR/Cas9 can be used to functionally cure the HIV disease by disrupting the CCR5 gene. It can also be used as a sterilizing cure by excising the HIV-1 genome from host cells. When applying this CRISPR/Cas9 anti-HIV technology into stem cells, the therapy can be long lasting and has the potential to help patients avoid lifelong ART treatments.
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