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Review

Regulation of hepatocyte cell cycle re-entry by RNA polymerase II-associated Gdown1

ORCID Icon & ORCID Icon
Pages 3222-3230 | Received 24 Aug 2020, Accepted 27 Sep 2020, Published online: 25 Nov 2020

Figures & data

Figure 1. Architecture of Pol II(G). (A) Schematic of Gdown1 functional domains. (B) Positions of TFIIF (blue) and TFIIB (yellow) relative to Gdown1 (purple) on Pol II (gray). (C) Location of Gdown1 functional domains determined by integrative structure modeling. Models based on data in [Citation32]

Figure 1. Architecture of Pol II(G). (A) Schematic of Gdown1 functional domains. (B) Positions of TFIIF (blue) and TFIIB (yellow) relative to Gdown1 (purple) on Pol II (gray). (C) Location of Gdown1 functional domains determined by integrative structure modeling. Models based on data in [Citation32]

Figure 2. Model for Gdown1 KO-induced cell cycle re-entry in liver. (A) A potential role of Gdown1 for gene transcription in normal liver. (B) A model for Gdown1 KO-induced cell cycle re-entry. Models based on data in [Citation42]

Figure 2. Model for Gdown1 KO-induced cell cycle re-entry in liver. (A) A potential role of Gdown1 for gene transcription in normal liver. (B) A model for Gdown1 KO-induced cell cycle re-entry. Models based on data in [Citation42]

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