Figures & data
Figure 1 A model of COPD progression and consequences. The multiple consequences of COPD, including breathlessness, exercise limitation, muscle wasting, fatigue, and exacerbations.
![Figure 1 A model of COPD progression and consequences. The multiple consequences of COPD, including breathlessness, exercise limitation, muscle wasting, fatigue, and exacerbations.](/cms/asset/374c57b8-c712-4c7a-9c33-9694d808868d/icop_a_358962_uf0001_b.gif)
Figure 2 Health status and FEV1. In clinical trials of the effect of treatment in COPD, the correlation between changes in FEV1 and SGRQ score is significant, but there is much scatter around the regression line. Source: (Citation[8]).
![Figure 2 Health status and FEV1. In clinical trials of the effect of treatment in COPD, the correlation between changes in FEV1 and SGRQ score is significant, but there is much scatter around the regression line. Source: (Citation[8]).](/cms/asset/437a642d-2d40-45ff-a19d-3586c09c812c/icop_a_358962_uf0002_b.gif)
Figure 3 SGRQ and FEV1 Slopes in the Obstructive Lung Disease (ISOLDE) trial (Citation[9]). Deterioration in SGRQ score was only weakly correlated with the decline in FEV1. Source for figure data: Spencer S, Calverley PM, Burge PS, et al. Impact of preventing exacerbations on deterioration of health status in copd. Eur Respir J. 2004;23:698–702 (Citation[9]).
![Figure 3 SGRQ and FEV1 Slopes in the Obstructive Lung Disease (ISOLDE) trial (Citation[9]). Deterioration in SGRQ score was only weakly correlated with the decline in FEV1. Source for figure data: Spencer S, Calverley PM, Burge PS, et al. Impact of preventing exacerbations on deterioration of health status in copd. Eur Respir J. 2004;23:698–702 (Citation[9]).](/cms/asset/f499334c-4731-4fac-81db-97198458bac4/icop_a_358962_uf0003_b.gif)
Table 1 Stepwise multivariate cox proportional hazards analysis to investigate the most significant predictor of mortality in male patients with chronic obstructive pulmonary disease
Figure 4 Withdrawal from treatment as an outcome in the ISOLDE study of COPD. The estimated rate of deterioration in COPD may be skewed by early withdrawal of patients with worse health or faster decline (Citation[19]).
![Figure 4 Withdrawal from treatment as an outcome in the ISOLDE study of COPD. The estimated rate of deterioration in COPD may be skewed by early withdrawal of patients with worse health or faster decline (Citation[19]).](/cms/asset/c38c2d00-89ce-4cb6-a9a1-7a8801ffd3ae/icop_a_358962_uf0004_b.gif)