Bronchiectasis: Phenotyping a Complex Disease

Figures & data

Figure 1. Impact of microbiology on annual exacerbation frequency in bronchiectasis (14). MRSA, Methicillin-resistant S. aureus.

Table 1. Outcomes in bronchiectasis patients with versus without Pseudomonas aeruginosa colonisation: meta-analysis of 21 observational cohort studies comprising 3683 patients.

Outcome	Odds ratio	95% CI	p-value
Mortality	2.95	1.98−4.40	p < 0.0001
Hospital admissions	6.57	3.19−13.51	p < 0.0001
Outcome	Mean difference	95% CI	p-value
Exacerbations	0.97/year	0.64−1.30	p < 0.0001
Quality of life^†	18.2 points	14.7−21.8	p < 0.0001

Constructed using data from (16).

^† Assessed by the St George's Respiratory Questionnaire.

Chalmers JD, Goeminne P, Aliberti S, McDonnell MJ, Lonni S, Davidson J, et al. The Bronchiectasis Severity Index. An international derivation and validation study. Am J Respir Crit Care Med 2014; 189(5):576−585.

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