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COPD: Journal of Chronic Obstructive Pulmonary Disease Volume 16, 2019 - Issue 3-4
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Original Articles

Clinical and Functional Characteristics of COPD Patients Across GOLD Classifications: Results of a Multicenter Observational Study

Dejan RadovanovicDepartment of Biomedical and Clinical Sciences (DIBIC), Università Degli Studi di Milano, Division of Pulmonary Diseases, Ospedale L. Sacco, ASST Fatebenfratelli-Sacco, Milan, Italy;
,
Marco ContoliSection of Internal and Cardiorespiratory Medicine, Department of Medical Sciences, University of Ferrara, Ferrara, Italy;
,
Fabiano Di MarcoDepartment of Health Sciences, Università Degli Studi di Milano, Respiratory Unit, ASST, Ospedale Papa Giovanni XXIII, Bergamo, Italy;
,
Giovanni SotgiuClinical Epidemiology and Medical Statistics Unit, Department of Medical, Surgical and Experimental Medicine, University of Sassari, Sassari, Italy;
,
Girolamo PelaiaDepartment of Medical and Surgical Sciences, Section of Respiratory Diseases, Magna Graecia University of Catanzaro, Catanzaro, Italy;
,
Fulvio BraidoRespiratory Disease and Allergy Clinic, Department of Internal Medicine, Ospedale Policlinico IRCCS San Martino di Genova, Italy;
,
Angelo Guido CorsicoDivision of Respiratory Diseases, IRCCS Policlinico San Matteo Foundation, Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy;
,
Claudio MichelettoUOC Pneumologia, Azienda Ospedaliera Universitaria Integrata, Verona, Italy;
,
Paola RoglianiDepartment of Experimental Medicine and Surgery, School of Respiratory Medicine, University of Rome Tor Vergata, Rome, Italy; ;Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Rome, Italy; ORCID Iconhttp://orcid.org/0000-0001-7801-5040
ORCID Icon,
Nicola ScichiloneDepartment of Biomedicine and Internal and Specialistic Medicine, University of Palermo, Palermo, Italy;
,
Laura SaderiClinical Epidemiology and Medical Statistics Unit, Department of Medical, Surgical and Experimental Medicine, University of Sassari, Sassari, Italy;
,
Pierachille SantusDepartment of Biomedical and Clinical Sciences (DIBIC), Università Degli Studi di Milano, Division of Pulmonary Diseases, Ospedale L. Sacco, ASST Fatebenfratelli-Sacco, Milan, Italy; Correspondence[email protected]
&
Paolo SolidoroCardiovascular and Thoracic Department, SC Pneumologia U, Città Della Salute e Della Scienza (Molinette) University Hospital, Turin, Italy
 show all
Pages 215-226 | Received 09 Apr 2019, Accepted 20 Aug 2019, Published online: 09 Sep 2019

Figures & data

Table 1. Clinical and functional characteristics of the study population.

Figure 1. Changes in the distribution of the ABCD groups from GOLD 2011 to GOLD 2017 within the study cohort.

Figure 1. Changes in the distribution of the ABCD groups from GOLD 2011 to GOLD 2017 within the study cohort.

Figure 2. Box plot showing the distribution of the forced expiratory volume in 1 second according to the GOLD 2017 subgroups.

Figure 2. Box plot showing the distribution of the forced expiratory volume in 1 second according to the GOLD 2017 subgroups.

Figure 3. Box plot showing the distribution of the inspiratory capacity according to the GOLD 2007, GOLD 2011 and GOLD 2017 criteria.

Figure 3. Box plot showing the distribution of the inspiratory capacity according to the GOLD 2007, GOLD 2011 and GOLD 2017 criteria.

Figure 4. Box plot showing the distribution of the lung diffusion capacity (DLCO) according to the GOLD 2007, GOLD 2011 and GOLD 2017 criteria.

Figure 4. Box plot showing the distribution of the lung diffusion capacity (DLCO) according to the GOLD 2007, GOLD 2011 and GOLD 2017 criteria.

Figure 5. Box plot showing the distribution of the alveolar volume (VA) and transfer coefficient (KCO) according to the GOLD 2007 staging criteria.

Figure 5. Box plot showing the distribution of the alveolar volume (VA) and transfer coefficient (KCO) according to the GOLD 2007 staging criteria.

Figure 6. Distribution of the clinical COPD phenotypes (mixed = dark grey, emphysema = grey, and chronic bronchitis = light grey) according to the GOLD 2007, GOLD 2011 and GOLD 2017 criteria.

Figure 6. Distribution of the clinical COPD phenotypes (mixed = dark grey, emphysema = grey, and chronic bronchitis = light grey) according to the GOLD 2007, GOLD 2011 and GOLD 2017 criteria.

Table 2. Distribution of the eosinophil counts and inhaled treatments according to the different GOLD classifications.

Table 3. Distribution of the eosinophil counts according to the patients’ clinical phenotype.

Table 4. Inhaled treatment distribution in frequent and non-frequent exacerbations.

Data availability statement

The data are available upon request.

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