2,005
Views
9
CrossRef citations to date
0
Altmetric
Articles

Obstructive Sleep Apnea Increases the Prevalence of Hypertension in Patients with Chronic Obstructive Disease

, , , , , , , , & show all
Pages 523-532 | Received 12 May 2020, Accepted 21 Aug 2020, Published online: 09 Sep 2020

Figures & data

Figure 1. Flowchart of study design and process.

Figure 1. Flowchart of study design and process.

Table 1. Patients’ baseline characteristics, sleep data, scores and comorbidities of the COPD only group and the OVS group.

Figure 2. The prevalence of hypertension increased with the increasing severity of OSA. A Chi-square test indicated that the prevalence of hypertension increased with the OSA severity (χ 2 = 19.364, p < 0.0001). There were no significant relationships between OSA severity and diabetes (χ 2 = 2.292, p = 0.541), coronary heart disease (χ 2 = 1.743, p = 0.628), arrhythmia (χ 2 = 3.398, p = 0.334) or cerebrovascular disease (χ 2 = 4.895, p = 0.182).

Figure 2. The prevalence of hypertension increased with the increasing severity of OSA. A Chi-square test indicated that the prevalence of hypertension increased with the OSA severity (χ 2 = 19.364, p < 0.0001). There were no significant relationships between OSA severity and diabetes (χ 2 = 2.292, p = 0.541), coronary heart disease (χ 2 = 1.743, p = 0.628), arrhythmia (χ 2 = 3.398, p = 0.334) or cerebrovascular disease (χ 2 = 4.895, p = 0.182).

Table 2. Prevalence rates of five comorbidities in COPD patients according to AHI (events/hour).

Figure 3. The prevalence of arrhythmia increased with the increasing severity of airflow limitation. A χ 2 test indicated that the prevalence of arrhythmia increased with the airway limitation severity (χ 2 = 30.835, p < 0.0001). There were no significant relationships between the varying degrees of airway limitation and hypertension (χ 2 = 5.271, p = 0.153), diabetes (χ 2 = 3.022, p = 0.388), coronary heart disease (χ 2 = 5.297, p = 0.151) or cerebrovascular disease (χ 2 = 1.245, p = 0.182).

Figure 3. The prevalence of arrhythmia increased with the increasing severity of airflow limitation. A χ 2 test indicated that the prevalence of arrhythmia increased with the airway limitation severity (χ 2 = 30.835, p < 0.0001). There were no significant relationships between the varying degrees of airway limitation and hypertension (χ 2 = 5.271, p = 0.153), diabetes (χ 2 = 3.022, p = 0.388), coronary heart disease (χ 2 = 5.297, p = 0.151) or cerebrovascular disease (χ 2 = 1.245, p = 0.182).

Table 3. Prevalence rates of five comorbidities in COPD patients according to the severity of airflow limitation.

Table 4. Results of logistic regression in analyzing the effect of OSA severity on comorbidities (Crude OR, 95% CI).

Table 5. Results of logistic regression in analyzing the effect of the severity of airflow limitation on comorbidities.

Table 6. Results of logistic regression used to explore risk factors for OSA in COPD patients.

Table 7. Results of logistic regression used to explore risk factors for hypertension.

Table 8. Results of logistic regression used to explore risk factors for arrhythmia.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.