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The Role of Blood Eosinophils in the Management of COPD: An Attempt to Answer the Important Clinical Questions

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Pages 690-699 | Received 27 Jul 2021, Accepted 22 Sep 2021, Published online: 18 Oct 2021

Figures & data

Figure 1. PubMed publications on blood eosinophils in COPD between 1991 and 2021 (accessed on July 20, 2021).

Figure 1. PubMed publications on blood eosinophils in COPD between 1991 and 2021 (accessed on July 20, 2021).

Figure 2. Pathogenetic mechanisms including the role of eosinophils in airways inflammation in COPD.

TSLP: Thymic stromal lymphopoietin; IL: Interleukin; ILC2: Type 2 innate lymphoid cell; ILC3: Type 3 innate lymphoid cell; TNFa: Tumor Necrosis Factor a; Tc1: Cytotoxic T cell; Th: T helper cell.

Figure 2. Pathogenetic mechanisms including the role of eosinophils in airways inflammation in COPD.TSLP: Thymic stromal lymphopoietin; IL: Interleukin; ILC2: Type 2 innate lymphoid cell; ILC3: Type 3 innate lymphoid cell; TNFa: Tumor Necrosis Factor a; Tc1: Cytotoxic T cell; Th: T helper cell.

Figure 3. Factors affecting the decision for the use of ICS in stable COPD, focusing on the role of blood eosinophil counts. Dashed line represents schematically blood eosinophils as a continuous variable.

AECOPD: acute exacerbations of COPD; BEC: blood eosinophil counts; FEV1: forced expiratory volume in 1 second.

Figure 3. Factors affecting the decision for the use of ICS in stable COPD, focusing on the role of blood eosinophil counts. Dashed line represents schematically blood eosinophils as a continuous variable.AECOPD: acute exacerbations of COPD; BEC: blood eosinophil counts; FEV1: forced expiratory volume in 1 second.

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