Performance in the Glittre-ADL Test is Associated with the Pulmonary Function of Patients with Chronic Obstructive Pulmonary Disease

Figures & data

Table 1. Anthropometric characteristics, lung function and functional capacity from total sample and GOLD classification.

Variables	Total Mean ± SD (n = 74)	GOLD 2 Mean ± SD (n = 16)	GOLD 3 Mean ± SD (n = 33)	GOLD 4 Mean ± SD (n = 25)
Age, years	66 ± 8	68 ± 8	65 ± 9	65 ± 8
Smoking history, pack years	59.9 ± 35.0	60.3 ± 38.2	56.6 ± 34.3	63.9 ± 34.8
Body mass, kg	72.0 ± 16.0	67.6 ± 17.5	74.4 ± 14.8	71.8 ± 16.4
Height, m	1.66 ± 0.10	1.64 ± 0.10	1.67 ± 0.10	1.67 ± 0.10
BMI, kg/m²	26.0 ± 4.8	24.8 ± 4.3	26.8 ± 4.8	25.7 ± 5.0
FEV1/FVC	0.44 ± 0.09	0.51 ± 0.07	0.46 ± 0.09	0.36 ± 0.06^#,&
FEV1, L	1.11 ± 0.46	1.68 ± 0.43	1.16 ± 0.29^#	0.69 ± 0.18^#,&
FEV1, %pred	37 ± 14	59 ± 6	38 ± 5^#	22 ± 4^#,&
FVC, L	2.48 ± 0.81	3.27 ± 0.70	2.55 ± 0.68^#	1.90 ± 0.55^#,&
FVC, %pred	65 ± 19	90 ± 11	65 ± 13^#	49 ± 11^#,&
6MWT, m	424 ± 93	463 ± 83	434 ± 88	387 ± 96^#
6MWT, %pred	77 ± 15	85 ± 13	78 ± 11	69 ± 16^#,&
TGlittre, min	4.7 ± 2.1	3.6 ± 0.8	4.2 ± 1.1	6.1 ± 2.9^#,&
TGlittre, %pred	157 ± 71	120 ± 24	138 ± 36	204 ± 98^#,&

SD, standard deviation; kg, kilograms; m, meters; BMI, body mass index; FEV₁, forced expiratory volume in first second; L, liter; %pred, percentage of predicted; FVC, forced vital capacity; min, minutes; 6MWT, six-minute walk test; TGlittre, Glittre-ADL test; ADL, activity of daily living.

^#p < .05 vs. GOLD 2.

^&p < .05 vs. GOLD 3.

Table 2. Correlation between lung function variables and functional tests performances.

Variable	6MWT (m)		6MWT (%pred)		TGlittre (min)		TGlittre (%pred)
	r	p	r	p	r	p	r	p
FEV1/FVC, L	0.40	<.001	0.45	<.001	−0.47	<.001	−0.53	<.001
FEV1, L	0.43	<.001	0.36	.001	−0.40	<.001	−0.44	<.001
FEV1, %pred	0.34	.003	0.40	<.001	−0.44	<.001	−0.46	<.001
FVC, L	0.28	.01	0.17	.14	−0.18	.12	−0.20	.09
FVC, %pred	0.20	.09	0.30	.01	−0.28	.01	−0.25	.03

6MWT, six-minute walk test; m, meter; %pred, percentage of predicted; TGlittre, Glittre-ADL test; ADL, activity of daily living; min, minutes; FEV₁, forced expiratory volume in first second; FVC, forced vital capacity; L, liter.

Table 3. Simple linear regression between lung function and functional tests, and predictor model for the 6MWT and Glittre-ADL test.

	Coefficient of regression	SE	95% CI	R²	p
6MWT, m
FEV1, L	86.1	21.2	43.8 to 128	0.17	<.001
FEV1, %pred	2.19	0.73	0.74 to 3.64	0.10	.004
FVC, L	32.6	13.0	6.68 to 58.5	0.07	.01
FVC, %pred	0.97	0.57	−0.17 to 2.12	0.02	.09
FEV1/FVC	394	106	183 to 604	0.15	<.001
Predictor model
Constant	329	25.6	277 to 380	–	<.001
FEV1, L	86.1	21.2	43.8 to 128	0.17	<.001
6MWT, %pred
FEV1, L	11.6	3.44	4.72 to 18.4	0.12	.001
FEV1, %pred	0.44	0.11	0.22 to 0.66	0.17	<.001
FVC, L	3.14	2.10	−1.04 to 7.33	0.02	.14
FVC, %pred	0.23	0.09	0.06 to 0.41	0.08	.01
FEV1/FVC	68.7	16.2	36.3 to 101	0.19	<.001
Predictor model
Constant	38.2	8.16	21.9 to 54.5	–	<.001
FEV1/FVC	62.0	16.2	29.7 to 94.3	0.22	<.001
FVC, %pred	0.17	0.08	0.01 to 0.34		.04
TGlittre, min
FEV1, L	−1.89	0.49	−2.86 to −0.91	0.16	<.001
FEV1, %pred	−0.07	0.01	−0.10 to −0.04	0.22	<.001
FVC, L	−0.68	0.30	−1.27 to −0.08	0.05	.03
FVC, %pred	−0.04	0.01	−0.07 to −0.02	0.14	.001
FEV1/FVC	−9.32	2.40	−14.1 to −4.55	0.16	<.001
Predictor model
Constant	7.37	0.61	6.15 to 8.60	–	<.001
FEV1, %pred	−0.07	0.01	−0.10 to −0.04	0.22	<.001
TGlittre, %pred
FEV1, L	−61.3	15.3	−91.80 to −30.8	0.17	<.001
FEV1, %pred	−2.38	0.48	−3.33 to −1.43	0.24	<.001
FVC, L	−20.2	9.46	−39.1 to −1.40	0.05	.04
FVC, %pred	−1.36	0.39	−2.13 to −0.58	0.13	.001
FEV1/FVC	−323	73.8	−470 to −176	0.20	<.001
Predictor model
Constant	241	19.0	203 to 279	–	<.001
FEV1, %pred	−2.38	0.48	−3.33 to −1.43	0.24	<.001

SE, standard error; 95% CI, 95% confidence interval; R², adjusted coefficient of determination; p, p value; 6MWT, six-minute walk test; m, meter; FEV₁, forced expiratory volume in first second; L, liter; FVC, forced vital capacity; %pred, percentage of predicted; TGlittre, Glittre-ADL test; ADL, activity of daily living.