Effect of Chemical Compositions and Topographical Features of Collagen Biofilms on Cell Response

ABSTRACT

The goal of this paper is to characterize new range of hybrid multicomponent polymer biofilms with collagen, synthetic poly-alcohols and hydroxiapatite, changing the components number, the ratio of each component, the open-pore, and the hydrophobic/hydrophilic material character. Films were obtained using a “casting solution method”. The cell viability was checked in all cases by the standard trypan blue exclusion text.

Keywords:

• cell growth
• collagen
• hydroxiapatite
• poly-vinyl alcohol

Acknowledgments

The authors would like to acknowledge Prof. Alex. Morega for assistance with Scan Program analysis. This work was financed on a Romanian CNCSIS Grant CH 440401 and Biotech National Program project no 4652.