https://orcid.org/0000-0003-0369-5269
Figures & data
Figure 1. CRISPR-Cas13 and its collateral activity.
Upon recognition of the target RNA by the crRNA (black), the activated Cas13 not only cleaves the target RNA (red) in cis but also cuts other nearby RNAs (blue) in trans.
Figure 2. Applications of dCas13.
dCas13 alone or its fusion with various effector domains allows precise manipulation of RNAs in eukaryotic cells.
Figure 3. Applications of Cas13 collateral activity.
Cas13 collateral activity has been used for nucleic acid detection, disease targeting and several other applications.
