Synthesis, Characterization, and Structural Studies of Nickel(II) Complexes of Some New Substituted Acid Hydrazides

Abstract

The syntheses, spectroscopic, magnetic, and antimicrobial and theoretical studies of a new series of hydrazides; RCOCH ₂ CONHNH ₂ (R = CH ₃ , C ₃ H ₇ , C ₆ H ₅ ) variously described as acetoacetic (AAAH), butyrylacetic (BUTAH) and benzoylacetic (BENZAH) acid hydrazides and its nickel(II) complexes are reported. Microanalyses, room temperature magnetic susceptibility measurements infrared and electronic reflectance spectra are consistent with a distorted six coordinate octahedral geometry for the complexes. The modeled compounds using semi-empirical method PM3 and density functional theory (DFT) shows a good correlation of crystallographic data. The compounds show appreciable activity against gram +ve and gram-ve bacteria.

Keywords:

• synthesis
• hydrazides
• structure
• spectroscopic

The authors are grateful to Ladoke Akintola University of Technology for financial support and Dr. Banjo Semire for useful discussions.