Nanosized MgO as a Heterogeneous Base Catalysts, Catalyses Multicomponent Reaction of Cyclic Enaminoketones, Malononitrile, and Aromatic Aldehydes

Abstract

Nanosized MgO is an efficient catalyst for the synthesis of 1,4-dihydropyridine and imidazo[1,2-a]quinoline derivatives from multicomponent reaction of cyclic enaminoketones, malononitrile and aromatic aldehydes in EtOH at reflux condition. This method provides several advantages such as mild reaction and high yield with short reaction time.

Keywords:

• nanosized MgO
• multicomponent reaction
• cyclic enaminoketones
• malononitrile
• aromatic aldehydes

Funding

The authors express their great appreciation to Kerman University of Medical Sciences, Pharmaceutics Research Center, Institute of Neuropharmacology, for support of this investigation.