https://orcid.org/0000-0002-9334-4405
Figures & data
Figure 1. Possible routes to counteract the age-induced decline of spermidine levels. With old age, endogenous spermidine concentrations diminish due to alterations in one or several factors that determine the bioavailability of the substance in the body. This detrimental decline may be counteracted by ingesting polyamine-rich food items, polyamine-enriched plant extracts, synthetic spermidine, or by stimulating polyamine synthesis in the gut microbiome through supplementation of prebiotics or probiotics.
