Figures & data
Table 1. Average absolute correlations across all probes of normalized methylation levels between relative pairs.
Figure 1. Distribution of maximal heritability estimates for DNA methylation of a) all probes (n = 472,494), b) significant probes (n = 13,621), c) FDR-corrected significant probes (n = 105).
Table 2. Heritability estimates.
Figure 2. Distribution of genetic heritability and common environmental effect of FDR-corrected significant probes (n = 105).
Figure 3. Circos plot depicting the distribution of maximal heritability estimates across the genome. Moving from inner to outer circles, first circle represents chromosomes. Maximal heritability of all 472,494 probes has been represented in second circle as scatter plot (values ranging from 0 to 100%). Third circle represents maximal heritability of the 105 FDR-corrected significant probes as scatter plot with genes name in which probes are located. Note: only 4 of the 5 genes (ARID3A, ARRDC2, MAST1, SCAMP4, and ZNF235) on chromosome 19 are shown due to place limitation.
Table 3. Overrepresented pathways identified among genes of FDR-corrected significant probes (n = 105).
