Figures & data
Table 1. Characteristics of neural tube defect cases and controls in stage 1 (n = 18)Footnotea.
Table 2. Distribution of genomic regions for significant CpG sites passing the stringent filtering criteriaFootnotea.
Figure 1. Hierarchical cluster analysis of the top 500 significantly differentially methylated CpG sites in neural tissues of NTD cases and controls of Population 1. Rows represent probes and columns represent samples. Cells are colored according to level of methylation (blue = low methylation, red = high methylation). The top 500 significant CpG sites can clearly distinguish lesion tissues from normal neural tissues.
Table 3. KEGG pathway analysis of the differentially methylated genes in neural tissues from NTD cases as compared to controlsFootnotea.
Table 4. Selection of differentially hypermethylated genes in neural tissues from NTD cases as compared to controls for validation using Sequenom MassARRAY in stage 1.
Table 5. Differentially methylated CpG sites in neural tissues of fetal mice with and without BaP exposure during ED 7.0–10.5Footnotea.
