Figures & data
Figure 1. HOX and epigenetic modifiers gene expression detected in AML patients.
Figure 2. Expression of specific HOX genes and related epigenetic modifiers in ATRA-sensitive and ATRA-resistant cell lines.
Figure 3. Histone mark changes upon ATRA and GSK-J4 inhibitor.
Figure 4. Enrichment of histone mark H3K27me3 on HOX gene promoters upon changes in JMJD3 expression.
Figure 5. Determination of differentiation and apoptotic status of APL cells upon ATRA and ATRA/GSK-J4 combination.
Figure 6. Scheme representing the HOX gene regulation by histone demethylation in PML-RARα- positive leukemia.
Supplemental material
