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Research Paper

Associations between placental CpG methylation of metastable epialleles and childhood body mass index across ages one, two and ten in the Extremely Low Gestational Age Newborns (ELGAN) cohort

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Pages 1102-1111 | Received 30 Mar 2019, Accepted 13 Jun 2019, Published online: 02 Jul 2019

Figures & data

Table 1. ELGAN (n = 889) and placental epigenetics sub cohort (n = 426) characteristics.

Table 2. Probes associated with changes in BMI z-score overall (n = 26 probes, representing 14 genes).

Table 3. Probes associated with changes in BMI z-score within placentas derived from female pregnancies (n = 26 probes, representing 15 genes).

Table 4. Probes associated with changes in BMI z-score within placentas derived from male pregnancies (n = 18 probes, representing 10 genes).

Figure 1. Distribution of CpG methylation at probe cg00702231, annotated to PLAGL1, within placentas derived from female pregnancies. Females were dichotomized as experiencing a change in BMI z-score that was above (n = 91) or below (n = 91) the median change in BMI z-score across ages one and ten (median = −0.08).

Figure 1. Distribution of CpG methylation at probe cg00702231, annotated to PLAGL1, within placentas derived from female pregnancies. Females were dichotomized as experiencing a change in BMI z-score that was above (n = 91) or below (n = 91) the median change in BMI z-score across ages one and ten (median = −0.08).
Supplemental material

Supplemental Material

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