Figures & data
Table 1. Study participant characteristics.
Table 2. List of all most significant association between DNA methylation and each sex hormone and SHBG at each sampling time point, respectively.
Figure 1. Manhattan plot (a) and Volcano plot (b) for the associations between DNA methylation and dehydroepiandrosterone estimated using mixed effects models.
Table 3. Differentially methylated regions calculated using the Comb-p method based on linear regression models. Restricted to regions overlapping between timepoints.
Table 4. Differentially methylated regions calculated using the Comb-p method based on mixed effects models.
Supplemental Material
Download Zip (1.1 MB)Data availability statement
The datasets generated and/or analysed during the current study are considered personal data, which prohibits us from storing them in a public depository. However, all data are archived at the Biobank Research Unit at Umeå University (https://www.umu.se/en/biobank-research-unit/research/access-to-samples-and-data/), and access for secondary use can be granted conditional upon meeting Swedish requirements for human research.